The Local Health System Sustainability Project (LHSS) is USAID's flagship initiative in integrated health systems strengthening. Its goal is to help low- and middle-income countries achieve strong, sustainable health systems as a means to support access to universal health coverage. Whether finding solutions to widely-shared challenges or providing tailored assistance for unique country needs, LHSS prioritizes engagement with diverse local actors. LHSS will equip countries to sustain health system progress after the project ends, supporting them in their journey to self-reliance.